The relationship between subjective sleep disturbance and attenuated psychotic symptoms after accounting for anxiety and depressive symptoms

MJC Formica; M Fuller-Tyszkiewicz; I Hickie; L Olive; SJ Wood; R Purcell; AR Yung; LJ Phillips; B Nelson; C Pantelis; PD McGorry; JA Hartmann

Journal article

The relationship between subjective sleep disturbance and attenuated psychotic symptoms after accounting for anxiety and depressive symptoms

MJC Formica, M Fuller-Tyszkiewicz, I Hickie, L Olive, SJ Wood, R Purcell, AR Yung, LJ Phillips, B Nelson, C Pantelis, PD McGorry, JA Hartmann

Schizophrenia Research | ELSEVIER | Published : 2023

DOI: 10.1016/j.schres.2023.07.019

Abstract

Background and hypotheses: Sleep disturbances are increasingly recognized as cooccurring with psychotic symptoms. The potential importance of this relationship is complicated when considering the effects of anxiety and depressive symptoms which commonly present in early-stage illness states. This study aimed to investigate the relationship between self-reported sleep disturbance on the development of attenuated psychotic symptoms (APS) cross-sectionally and longitudinally while adjusting for roles of anxiety and depressive symptoms. Design: Eight-hundred and two help-seeking young people aged 12 to 25 years who engaged with our Australian early intervention services were included in the stud..

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University of Melbourne Researchers

Stephen Wood Author

Rosemary Purcell Author

Lisa Phillips Author

Barnaby Nelson Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council (NHMRC) Program grants 350241 and 566529 (ARY, PDM, SJW) and the Colonial Foundation. P.D.M. was supported by a Senior Principal Research Fellowship from the NHMRC (ID: 1060996). A.R.Y., and B.N. were supported by NHMRC Senior Research Fellowships (IDs: 566593, 1137687). J.H. was supported by a McKenzie Fellowship, The University of Melbourne. S.J.W. was supported by an NHMRC Clinical Career Developmental Award (359223). MF was supported by an Australian Government Research Training Program Scholarship. MFT and LO are supported by The Centre for Social and Early Emotional Development (SEED), Faculty of Health, Deakin University.